Partial characterization of the K88ab fimbria epitope of Escherichia coli (ECET) recognized by a monoclonal antibody directed towards adhesin

  • Ana Campal Espinosa Centro de Ingeniería de Genética y Biotecnología de Camagüey, Cuba
  • María Castro Santana Centro de Ingeniería de Genética y Biotecnología de Camagüey, Cuba
  • Jesús Junco Barranco Centro de Ingeniería de Genética y Biotecnología de Camagüey, Cuba
  • Sonia Casas Suárez Centro de Ingeniería de Genética y Biotecnología de Camagüey, Cuba

Abstract

A conformable epitope was partially characterized at  the  “b” region of enterotoxigenic Escherichia coli K88ab.  The epitope is recognized by the  monoclonal antibody secreted by  the   hybridoma  11/70.   The   specificity  of  the   monoclonal  antibody  for  antigen detection,  was defined by the  ELISA test  and  agglutination  with  fimbrial  bacteria.  Mab 11/70  proved  its usefulness to design diagnosis systems for epizootiological studies as an essential tool for vaccination against ETEC strains in swine breeding farms.

 

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Published
2019-10-17
How to Cite
Campal Espinosa, A., Castro Santana, M., Junco Barranco, J., & Casas Suárez, S. (2019). Partial characterization of the K88ab fimbria epitope of Escherichia coli (ECET) recognized by a monoclonal antibody directed towards adhesin. Revista De Producción Animal, 15(2). Retrieved from https://revistas.reduc.edu.cu, revistas.reduc.edu.cu/index.php/rpa/article/view/3188
Issue
Vol 15 No 2 (2003): Julio-Diciembre
Section
Salud Animal

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