Evaluation of Anti-Microbial Activity of Extracts of Moringa oleifera Lam. Cultivated in Cuba

  • Raisa Monteagudo Borges Research Laboratory. “Moringa as a nutritional supplement” Project, Center for Research on Protein Plants and Bionatural Products. https://orcid.org/0000-0002-4926-8783
  • Odalys Fidalgo Perera Finlay Vaccine Institute. https://orcid.org/0000-0003-0015-4061
  • Ernesto Almora Hernández Research Laboratory. “Moringa as a nutritional supplement” Project, Center for Research on Protein Plants and Bionatural Products. https://orcid.org/0000-0002-1431-7004
  • Vivian Lago Abascal Research Laboratory. “Moringa as a nutritional supplement” Project, Center for Research on Protein Plants and Bionatural Products. https://orcid.org/0000-0002-3229-1872
  • Olga Echemendia Arana Research Laboratory. “Moringa as a nutritional supplement” Project, Center for Research on Protein Plants and Bionatural Products. https://orcid.org/0000-0002-2916-1524
  • Graciela Bolaños Queral Finlay Vaccine Institute. https://orcid.org/0000-0001-5829-8645

Abstract

Background: Moringa oleifera (Moringaceae) is a highly praised plant that has spread in many tropical and subtropical countries. It has an impressive variety of medicinal uses with a high medicinal value. Aim. To evaluate the in vitro anti-microbial activity of aqueous and hydro-alcoholic extracts of Moringa oleifera Lam. cultivated in Cuba. Methods: The MTT method was used to evaluate in vitro cytotoxicity and antiviral activity of different concentrations of the extracts from dry leaves of Moringa oleifera against Type 1 Herpes Simplex Virus (HSV-1), and type 2 Herpes Simplex Virus (HSV-2). The determinations were made by microdilution, antimicrobial activity against the reference bacterial strains, and clinical isolates, then the minimum inhibitory concentration was calculated (MIC). Results: The hydroalcoholic extract showed toxicity at the 125 μg/ml concentration, whereas the aqueous extract stopped being toxic at 500 μg/ml in the Vero cells within the range of the concentrations evaluated. None of the extracts inhibited the in vitro replication of the HSV-1 and HSV-2 viruses, but they showed a powerful activity against the bacterial strains and yeast assayed at different levels. Conclusions: The extracts did not show in vitro antiviral activity against HSV-1 and HSV-2 in Vero cells, whereas the antibacterial activity was strong, suggesting that the leaves of Moringa oleifera might be a good candidate for an antibacterial agent from natural products against the different pathogens.

Keywords: Antimicrobial activity, antiviral, herpes simplex, Moringa oleifera Lam. (Source: NAL-USDA)

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Published
2022-04-05
How to Cite
Monteagudo Borges, R., Fidalgo Perera, O., Almora Hernández, E., Lago Abascal, V., Echemendia Arana, O., & Bolaños Queral, G. (2022). Evaluation of Anti-Microbial Activity of Extracts of Moringa oleifera Lam. Cultivated in Cuba. Revista De Producción Animal, 34(1). Retrieved from https://revistas.reduc.edu.cu, revistas.reduc.edu.cu, revistas.reduc.edu.cu, revistas.reduc.edu.cu, revistas.reduc.edu.cu, revistas.reduc.edu.cu, revistas.reduc.edu.cu, revistas.reduc.edu.cu/index.php/rpa/article/view/e4153
Issue
Vol 34 No 1 (2022): January-April. In progress
Section
Manejo y Alimentación

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